ABOUT US

WHO WE ARE

CRISPNA Bio is a biotechnology company based on CRISPNA technology (PCT/EP2021/087887), a patent developed by two research groups from the University of Granada. 

CRISPNA technology combines the versatility of CRISPR/Cas systems with the specificity, stability, and sensitivity of peptide nucleic acids (PNAs). The idea is to use PNAs (rather than RNA) to direct Cas proteins to their DNA or RNA targets. CRISPNA technology can be applied in a variety of fields, including gene therapy, diagnostics, and biotechnology.

 In gene therapy, CRISPNA technology can be used to edit or remove specific genes of therapeutic interest. In diagnosis, CRISPNA technology can be used to develop detection systems for tumor or infectious markers. In biotechnology, CRISPNA technology can be used to develop new products and processes.

OUR PURPOSE

Our MISSION is to bring CRISPNA technology to market, and consolidate our CRISPNA technology for different CRISPR application as gene therapy and diagnosis.

CRISPR/Cas in Gene Therapy. In the field of gene therapy, the different CRISPR/Cas systems have become a powerful tool for the treatment of both monogenetic diseases and acquired diseases such as cancer or infectious diseases. These systems can be used to correct mutations, remove genes necessary for the disease process (receptors for infectious agents, oncogenes), replace mutated genes, or to safely introduce therapeutic genes so that they can compensate for deficiencies in cell function. GE has transformed the way in which gene therapy is approached, from being based exclusively on the introduction of exogenous genes and non-specific and uncontrolled genome modifications, to being able to precisely control the modifications that are made in the cells of the patients. CRISPR/Cas systems are currently being investigated in patients, with more than 100 clinical trials in different monogenetic diseases, cancer and infectious diseases. 5 of these trials are already in phase III, all of them for the treatment of beta-thalassemia or sickle cell disease. Another 18 are already in phase 2 for the treatment of different types of cancer and infectious diseases (COVID, AIDS) and monogenic diseases (hereditary angioderma and Leber’s disease))

OUR HISTORY

CRISPNA bio is funded in 2021 based on CRISPNA technology, a patent developed by two research groups from the University of Granada. We have facilities for molecular analysis, cell biology, small animal research and cell-culture facilities with P2-level safety. In addition, our team is working in collaboration with several academic labs and companies to validate our CRISPNA technology to create an alternative more stable, specific and robustness than CRISPR/Cas system.

Founder Team

Franscisco Martín (PhD)

Main Founder & Chief of Advisory Board of LentiStem -University of Granada-

Juan José Díaz Mochón (PhD)

-University of Granada, CSO of DestINA Genomics-

Rosario Sánchez
(PhD)

-University of Granada, Chief of the Advisory Board of NanoGetics

Araceli Aguilar-González(PhD)

-University of Granada/GENYO-

Carlos Martín
(MBA)

Co-founder & CEO of LentiStem

Noelia Maldonado-Pérez (PhD)

University of Geneva

María Tristán-Manzano
(PhD)

Co-founder & CSO of LentiStem

Pedro Justicia
(PhD)

Manager of R&D of LentiStem

Julia Martínez

CAO of LentiStem “Tax and accounting advisor”

Board of directors

Franscisco Martín (PhD)

Co-founder, Board member & Chair of the Board

Juan José Díaz Mochón (PhD)

Co-Founder & board member

Rosario Sánchez
(PhD)

Co-founder and board member

Araceli Aguilar-González(PhD)


Co-Founder & Chief Scientific Officer

Carlos Martín
(MBA)

Co-founder & CEO

Team

Araceli Aguilar-González(PhD)​

Co-founder & CSO

Pedro Justicia
(PhD)

Co-founder & I+D member​​

María Tristán-Manzano (PhD)

Co-founder & I+D member​

Noelia Maldonado-Pérez (PhD)

Co-founder & I+D member

Financial Team

Carlos Martín (MBA)

Co-founder & CEO

Julia Martínez

CAO of LentiStem “Tax and accounting advisor”